Background: The poly-Glycine-Serine (G4S) linker is a type of flexible, unstructured synthetic peptide linker sequence often leveraged to connect antibody fragments (scFvs) and fusion proteins . The linker itself consists of a core pentapeptide sequence, Gly-Gly-Gly-Gly-Ser, that is repeated and commonly found as either a 15-mer (G4S)3 or 20-mer (G4S)4 within scFv-based CARs and scFv fragments. The linker sequence length plays a role in controlling scFv stability and the noncovalent association between the VH and VL domains.Anti-(G4S)4 antibody(BM1049) can binds to linkers with more than one repeat of GGGGS peptide.
Description: PE-conjugated Anti-(G4S)4 antibody(BM1049), Rabbit mAb
Storage & Shipping: Store at 2°C-8°C for 6 months
Formulation & Reconstitution: Liquid，PBS with 0.05% Proclin300, 1% BSA
Target: G4S linker
Uniprot ID: N/A
Usage: Research use only
Clone ID: BM1049
Purification: Purified from cell culture supernatant by affinity chromatography
Recommended Dilutions: Flow Cyt 1:100
Deutsch
English
