Pentaacetylquercetin, CAS 1064-06-8

Shelf life (days): 730.0

Formulation: A crystalline solid

Formal Name: 3,5,7-tris(acetyloxy)-2-[3,4-bis(acetyloxy)phenyl]-4H-1-benzopyran-4-one

Purity: ≥95%

Formula Markup: C25H20O12

Formula Weight: 512.4191

CAS Number: 1064-06-8

Notes: Pentaacetylquercetin is a pentaacetylated derivative of the flavonoid quercetin (Item No. 10005169) that has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties.{45115,45116,45117} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in vitro (IC50 = 3.74 μg/ml) and inhibits iron(II) chloride-induced lipid peroxidation in rat liver mitochondria (IC50 = 20.2 μg/ml).{45115} Pentaacetylquercetin inhibits LPS-induced increases in nitrite (IC50 = 8.7 μM) and PGE2 (Item No. 14010) production, as well as inducible nitric oxide synthase (iNOS) and COX-2 levels, in RAW 264.7 cells when used at concentrations of 20 and 40 μM.{45116} It also inhibits the growth of HL-60, U937, and SK-MEL-1 cells (IC50s = 38, 25, and 58 μM, respectively).{45117}

• Artikelnummer: CAY26694-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 26694-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK