Pentabromopseudilin, CAS 10245-81-5

Product Description: Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour and phytotoxic activities. PBrP is a reversible and allosteric inhibitor of myosin Va (MyoVa). PBrP also is a potent inhibitor of transforming growth factor-β (TGF-β) activity. PBrP can be used for the research of fibrotic diseases and cancer[1].

Applications: Cancer-Kinase/protease

Formula: C10H4Br5NO

References: [1]Shih-Wei W, et al. Pentabromopseudilin: a myosin V inhibitor suppresses TGF-β activity by recruiting the type II TGF-β receptor to lysosomal degradation. J Enzyme Inhib Med Chem. 2018;33(1):920-935.

CAS Number: 10245-81-5

Molecular Weight: 553.66

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Antibiotic;TGF-β Receptor

• Artikelnummer: MEXHY-113604-500UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-113604-500UG
• Verpackungseinheit: 500 μg
• Mengeneinheit: STK