PF-06747711, CAS 1892576-58-7

Product Description: PF-06747711 is a potent, selective, and orally active retinoic acid receptor-related orphan C2 (RORC2, also known as RORγt) inverse agonist, with an IC50 of 4.1 nM. Anti-skin inflammatory activity[1].

Applications: COVID-19-immunoregulation

Formula: C26H26F3N5O2

References: [1]Schnute ME, et al. Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist. J Med Chem. 2018 Sep 9.

CAS Number: 1892576-58-7

Molecular Weight: 497.51

Compound Purity: 99.86

Research Area: Inflammation/Immunology

Solubility: DMSO : 41.67 mg/mL (ultrasonic)

Target: ROR

• Artikelnummer: MEXHY-112706-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-112706-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK