Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 2-methyl-N-[(1S)-2-(methylphenylamino)-2-oxo-1-(phenylmethyl)ethyl]-1H-indole-3-acetamide
Purity: ≥98%
Formula Markup: C27H27N3O2
Formula Weight: 425.5223
CAS Number: 1352879-65-2
Notes: PF-3450074 (PF74) is an inhibitor of HIV-1 capsid protein.{62553} It reduces viral infectivity in HeLa cells infected with wild-type HIV-1 but not P38A, E45A, Q63A/Q67A, or Q219A capsid protein mutant HIV-1, simian immunodeficiency virus, or murine leukemia virus when used at a concentration of 10 µM. PF74 (0.62-10 µM) reduces capsid protein levels in HIV-1 viral cores.