PF-AKT400, CAS 1004990-28-6

Product Description: PF-AKT400 is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0.5 nM) than PKA (IC50=450 nM).

Applications: Cancer-Kinase/protease

Formula: C20H22F2N6O

References: [1]Chen SF, et al. Binding selectivity studies of PKBα using molecular dynamics simulation and free energy calculations. J Mol Model. 2013 Nov;19(11):5097-5112./[2]Freeman-Cook KD, et al. Design of selective, ATP-competitive inhibitors of Akt. J Med Chem. 2010 Jun 24;53(12):4615-4622.

CAS Number: 1004990-28-6

Molecular Weight: 400.43

Compound Purity: 98.0

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: Akt

• Artikelnummer: MEXHY-10721-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-10721-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK