Conjugation: HRP: Horseradish Peroxidase
Description of Target: PHACTR3 is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1.The protein encoded by this gene is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms.
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PHACTR3
Key Reference: Worch,S., (2006) Cytogenet. Genome Res. 115 (1), 23-29
Molecular Weight: 51kDa
Peptide Sequence: Synthetic peptide located within the following region:
IEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Phosphatase and actin regulator 3
Protein Size: 448
Purification: Affinity Purified
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