Target Synonym: PHF20;C20orf104;GLEA2;HCA58;NZF;TDRD20A;TZP
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Immunogen: Recombinant fusion protein of human PHF20
Dilution: WB 1:500-1:2000
Calculated MW: 31kDa/115kDa
Observed MW: 115kDa