PHGDH-inactive, CAS 1914971-16-6

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-(4,6-dimethyl-2-pyridinyl)-4-(4-pyridinyl)-1-piperazinecarbothioamide

Purity: ≥98%

Formula Markup: C17H21N5S

Formula Weight: 327.5

CAS Number: 1914971-16-6

Notes: PHGDH-inactive is an inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 (Item No. 19716) and NCT-503 (Item No. 19718).{31375} Unlike the inhibitors, PHGDH-inactive does not inhibit PHGDH in vitro (IC50s = >57, 3.7, and 2.5 µM for PHGDH-inactive, NCT-502, and NCT-503, respectively), block serine synthesis in cells, or kill PHGDH-dependent cell lines.{31375} PHGDH-inactive is intended to serve as a negative control for NCT-502 and NCT-503.

• Artikelnummer: CAY19717-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 19717-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK