Philanthotoxin 74 dihydrochloride, CAS 1227301-51-0

Philanthotoxin 74 dihydrochloride, CAS 1227301-51-0
Artikelnummer
MEXHY-104020A-1
Verpackungseinheit
1 mg
Hersteller
MedChemExpress

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Product Description: Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C24H44Cl2N4O3

References: [1]Poulsen MH, et al. Evaluation of PhTX-74 as subtype-selective inhibitor of GluA2-containing AMPA receptors. Mol Pharmacol. 2014 Feb;85(2):261-8./[2]Kromann H, et al. Solid-phase synthesis of polyamine toxin analogues: potent and selective antagonists of Ca2+-permeable AMPA receptors. J Med Chem. 2002 Dec 19;45(26):5745-54.

CAS Number: 1227301-51-0

Molecular Weight: 507.54

Compound Purity: 99.72

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 50 mg/mL (ultrasonic)

Target: iGluR
Mehr Informationen
Artikelnummer MEXHY-104020A-1
Hersteller MedChemExpress
Hersteller Artikelnummer HY-104020A-1
Verpackungseinheit 1 mg
Mengeneinheit STK
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