Philanthotoxin 74 (hydrochloride), CAS 1227301-51-0

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-[7-[(4-aminobutyl)amino]heptyl]-4-hydroxy-aS-[(1-oxobutyl)amino]-benzenepropanamide, dihydrochloride

Purity: ≥98%

Formula Markup: C24H42N4O3 / 2HCl

Formula Weight: 507.5

CAS Number: 1227301-51-0

Notes: Philanthotoxin 74 (PhTx-74) is a synthetic analog of the naturally-occurring wasp venom toxin philanthotoxin-4,3,3. It is a subtype-selective AMPA receptor antagonist that inhibits homomeric GluR1 and GluR3 as well as heteromeric GluR1/2 receptors (80-100% of glutamate-evoked currents inhibited at 100 µM). It exhibits minimal to no effect on monomeric GluR2 or heteromeric GluR2/3 receptors at concentrations up to 500 µM.{23500} PhTx-74 inhibits the GluR5(Q) receptor with a Ki value of 0.29 µM.{23501}

• Artikelnummer: CAY14607-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 14607-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK