Product Description: Phthalide is a chemical scaffold. Phthalide can be used to synthesize a variety of phthalide derivatives including anti-inflammatory agent, antimicrobial, antioxidant and blood-tumor barrier modulators[1][2][3][4].
Applications: COVID-19-immunoregulation
Formula: C8H6O2
References: [1]Liu Zeng Chen, et al. Novel phthalide derivatives: Synthesis and anti-inflammatory activity in vitro and in vivo. Eur J Med Chem. 2020 Nov 15;206:112722./[2]Chakapong Intaraudom, et al. Antimicrobial drimane - phthalide derivatives from Hypoxylon fendleri BCC32408. Fitoterapia. 2019 Oct;138:104353./[3]Xin Fang, et al. Synthesis of phthalide derivatives and evaluation on their antiplatelet aggregation and antioxidant activities. J Asian Nat Prod Res. 2020 Dec;22(12):1176-1187./[4]Liu X, et al. Six Phthalides as Potent Modulators of the Blood Tumor Barrier Increase the Transmembrane Transport of Compatible Compounds Via Transcellular and Paracellular Pathways. Pharmaceutical Chemistry Journal, 2024, 57(12): 1967-1976.
CAS Number: 87-41-2
Molecular Weight: 134.13
Compound Purity: 99.95
Research Area: Cancer; Infection; Inflammation/Immunology; Cardiovascular Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 2 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Bacterial;Biochemical Assay Reagents
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