Pifithrin-α, CAS 63208-82-2

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)-ethanone, monohydrobromide

Purity: ≥95%

Formula Markup: C16H18N2OS / HBr

Formula Weight: 367.30494

CAS Number: 63208-82-2

Notes: Pifithrin-α is an inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis.{17259} It prevents p53-mediated apoptosis induced by cytotoxic compounds in C8 cells at 10 μM {17259} and in human umbilical vein endothelial cells at 30 μM.{17260} Pifithrin-α can also protect cells from DNA damage-induced apoptosis by a p53-independent mechanism that might involve cyclin D1.{17261}

• Artikelnummer: CAY13326-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 13326-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK