Product Description: Pimecrolimus (SDZ-ASM 981) is a potent, nonsteroid and orally active calcineurin inhibitor with a Ki of 117 nM. Pimecrolimus shows anti-inflammatory activity[1][2].
Applications: COVID-19-immunoregulation
Formula: C43H68ClNO11
References: [1]Grassberger M, et al. Pimecrolimus -- an anti-inflammatory drug targeting the skin. Exp Dermatol. 2004 Dec;13(12):721-30./[2]Grassberger M, et al. A novel anti-inflammatory drug, SDZ ASM 981, for the treatment of skin diseases: in vitro pharmacology. Br J Dermatol. 1999 Aug;141(2):264-73./[3]Meingassner JG, et al. A novel anti-inflammatory drug, SDZ ASM 981, for the topical and oral treatment of skin diseases: in vivo pharmacology. Br J Dermatol. 1997 Oct;137(4):568-76.
CAS Number: 137071-32-0
Molecular Weight: 810.45
Compound Purity: 98.0
Research Area: Inflammation/Immunology
Solubility: DMSO : ≥ 32 mg/mL
Target: Phosphatase
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