Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (2E)-1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenyl-2-propen-1-one
Purity: ≥98%
Formula Markup: C16H14O4
Formula Weight: 270.284
CAS Number: 18956-15-5
Notes: A chalcone with diverse biological activities; reduces ferric to ferrous iron in a FRAP assay (IC50 = 334 µM); inhibits α-glucosidase (IC50 = 12.94 µM); decreases the proliferation of L. amazonensis at 1 µg/ml; cytotoxic to KB, MCF-7, Ca Ski, and HCT116 cells (IC50s = 6.2, 7.3, 7.7, and 54.1 µM, respectively); inhibits LPS-induced increases in TNF-α and IL-1β in J774A.1 macrophages (IC50s = 69 and 43 µM, respectively)