Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 2-(3,4-dihydroxyphenyl)ethyl 3-O-ß-D-glucopyranosyl-ß-D-glucopyranoside 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
Purity: ≥95%
Formula Markup: C29H36O16
Formula Weight: 640.58654
CAS Number: 104777-68-6
Notes: Plantamajoside is a phenylethanoid that has been found in P. lanceolata and has diverse biological activities, including antioxidative, anticancer, and anti-inflammatory properties.{45282,45283,45284} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC50 = 11.8 µM). It also inhibits 5-lipoxygenase (5-LO) and 15-LO (IC50s = 0.375 and 96 µM, respectively).{45282,45283} Plantamajoside decreases viability of TE-1 esophageal squamous cell carcinoma (ESCC) cells when used at concentrations ranging from 20 to 320 µg/ml, as well as inhibits LPS-induced epithelial-to-mesenchymal transition (EMT) in Eca-109 and TE-1 cells and decreases phosphorylated NF-κB levels in TE-1 cells.{45284} Plantamajoside (3 mg/ear) inhibits mouse ear edema induced by arachidonic acid (Item Nos. 90010 / 90010.1 / 10006607) by 25%.{45282}
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