Description: Plerixafor octahydrochloride (JM3100 octahydrochloride) blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow and HSC movement into the peripheral circulation. Plerixafor is a bicyclam with hematopoietic stem cell-mobilizing activity.
CAS Number: 155148-31-5
Formula: C28H62Cl8N8
Molecular Weight: 794,46
References: Zabel BA, et al. J Immunol. 2009, 183(5), 3204-3211.