PNU 112455A, CAS 21886-12-4

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 4-[(6-amino-4-pyrimidinyl)amino]-benzenesulfonamide, monohydrochloride

Purity: ≥95%

Formula Markup: C10H11N5O2S / HCl

Formula Weight: 301.75348

CAS Number: 21886-12-4

Notes: PNU 112455A is an inhibitor of cyclin-dependent kinase 2 (Cdk2) and Cdk5 (Ki = 2 µM for both).{63141} It inhibits hyperphosphorylation of tau and cell death induced by the synthetic glucocorticoid dexamethasone (Item No. 11015) in PC12 rat adrenal medulla cells expressing human tau when used at concentrations of 1 and 10 µM.{63142}

• Artikelnummer: CAY33438-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33438-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK