Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) (PODXL/2185), CF740 conjugate, 0.1mg/mL

Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) (PODXL/2185), CF740 conjugate, 0.1mg/mL
Artikelnummer
BTMBNC742185-100
Verpackungseinheit
100 uL
Hersteller
Biotium

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Description: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is highly expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: PODXL/2185

Immunogen: Recombinant fragment of human Podocalyxin (around aa 310-447) (exact sequence is proprietary)

Antibody Reactivity: Podocalyxin

Entrez Gene ID: 5420

Z-Antibody Applications: IHC, FFPE (verified)

Verified AB Applications: IHC (FFPE) (verified)

Antibody Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody/Immunohistology (formalin): 1-2 ug/mL for 30 minutes at RT/Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes/Optimal dilution for a specific application should be determined by user
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Artikelnummer BTMBNC742185-100
Hersteller Biotium
Hersteller Artikelnummer BNC742185-100
Verpackungseinheit 100 uL
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunohistochemistry
Isotyp IgG1
Wirt Mouse
Konjugat Conjugated, CF740
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