Application Note: WB: 1:500-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 58
Form: Liquid
Buffer (with preservative): PBS, 150mM NaCl, 50% Glycerol, 0.02% sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Uniprot ID: P78395
Antigen Species: Human
Immunogen: A synthesized peptide derived from human PRAME(Accession P78395), corresponding to amino acid residues W481-C505.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: preferentially expressed antigen in melanoma
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