PRIMA-1, CAS 5608-24-2

Shelf life (days): 365.0

Formulation: A crystalline solid

Formal Name: 2,2-bis(hydroxymethyl)-3-quinuclidinone

Purity: ≥95%

Formula Markup: C9H15NO3

Formula Weight: 185.2

CAS Number: 5608-24-2

Notes: Mutations in the p53 tumor suppressor are found in many different neoplastic cells. PRIMA-1 restores sequence-specific DNA binding and transactivational activity to mutant p53 proteins at relatively high µM to mM concentrations.{9837} It is therefore a unique anti-oncogenic substance, working as a re-activator of the apoptotic function of mutant p53 via conformational modulation of function-specific epitopes. PRIMA-1 represents a novel lead compound which may be further modified to provide more potent therapeutic agents acting via the reactivation mechanism.

• Artikelnummer: CAY63520-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 63520-50
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK