Clone Name: AT1D10
Light Chain: Kappa
Application Note: WB: 1:500-1:5000. ICC/IF: 1:100. FCM: 2-5μg for 1x 10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 29
Form: Liquid
Buffer (with preservative): PBS, 10% Glycerol, 0.02% Sodium Azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Uniprot ID: P07288
Antigen Species: Human
Immunogen: Recombinant human KLK3(25-261aa) purified from E. coli
Purification: Purified by Protein G
Conjugation: Unconjugated
Full Name: kallikrein related peptidase 3