PSI-697, CAS 851546-61-7

Product Description: PSI-697 is an oral P-selectin inhibitor with an IC50 of 125 μM[1].

Applications: Cancer-programmed cell death

Formula: C21H18ClNO3

References: [1]Bedard PW et al. Characterization of the novel P-selectin inhibitor PSI-697 [2-(4-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h] quinoline-4-carboxylic acid] in vitro and in rodent models of vascular inflammation and thrombosis. J Pharmacol Exp Ther./[2]Myers DD Jr et al. Resolution of venous thrombosis using a novel oral small-molecule inhibitor of P-selectin (PSI-697) without anticoagulation. Thromb Haemost. 2007 Mar;97(3):400-7./[3]Myers DD Jr et al. Treatment with an oral small molecule inhibitor of P selectin (PSI-697) decreases vein wall injury in a rat stenosis model of venous thrombosis. J Vasc Surg. 2006 Sep;44(3):625-32.

CAS Number: 851546-61-7

Molecular Weight: 367.83

Compound Purity: 99.73

Research Area: Cancer

Solubility: DMSO : ≥ 45.8 mg/mL

Target: P-selectin

• Artikelnummer: MEXHY-15526-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15526-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK