Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (2Z)-2-methyl-2-butenoic acid, (9R,10R)-9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10-yl ester
Purity: ≥98%
Formula Markup: C21H22O7
Formula Weight: 386.39518
CAS Number: 13161-75-6
Notes: Pteryxin is a coumarin that has been found in A. furcijuga and has diverse biological activities.{46928,46927,46929,46930} It inhibits LPS-induced nitric oxide production in mouse peritoneal macrophages (IC50 = 20 µM).{46928} Pteryxin (100 µg/ml) completely inhibits collagen-induced aggregation of isolated rabbit platelets.{46927} It inhibits butyrylcholinesterase (BChE; IC50 = 12.96 µg/ml).{46929} Pteryxin reduces triacylglycerol levels and expression of the genes encoding sterol regulatory element binding protein 1c (SREBP-1c), fatty acid synthase (FASN), and acetyl-coenzyme A carboxylase 1 (ACC1) in 3T3-L1 adipocytes and HepG2 cells.{46930}
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