Pyruvate dehydrogenase kinase 1 / PDK1 blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89378.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Background: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]

Region Sequence: C-DFKDKSAEDAK

Full Name: pyruvate dehydrogenase kinase 1

• Artikelnummer: GTX89378-PEP-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX89378-PEP-100
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Human Gene ID: 5163