Product Description: Quercetin dihydrate, a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively[1].
Applications: COVID-19-immunoregulation
Formula: C15H14O9
References: [1]Navarro-Núñez L, et al. Effect of quercetin on platelet spreading on collagen and fibrinogen and on multiple platelet kinases. Fitoterapia. 2010 Mar;81(2):75-80./[2]Yu XB, et al. Inhibitory effects of protein kinase C inhibitors on tumor necrosis factor induced bovine pulmonary artery endothelial cell injuries. Yao Xue Xue Bao. 1996;31(3):176-81./[3]Yang F, et al. Combination of Quercetin and 2-Methoxyestradiol Enhances Inhibition of Human Prostate Cancer LNCaP and PC-3 Cells Xenograft Tumor Growth. PLoS One. 2015 May 26;10(5):e0128277.
CAS Number: 6151-25-3
Molecular Weight: 338.268
Compound Purity: 97.0
Research Area: Inflammation/Immunology; Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL
Target: Apoptosis;PI3K
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