Product Description: Quisqualic acid (L-Quisqualic acid), a natural analog of glutamate, is a potent and pan two subsets (iGluR and mGluR) of excitatory amino acid (EAA) agonist with an EC50 of 45 nM and a Ki of 10 nM for mGluR1R. Quisqualic acid is isolated from the fruits of Quisqualis indica[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C5H7N3O5
References: [1]Hugues-Olivier Bertrand, et al. Common and Selective Molecular Determinants Involved in Metabotopic Glutamate Receptor Agonist Activity. J Med Chem. 2002 Jul 18;45(15):3171-83./[2]H Bräuner-Osborne, et al. Ligands for Glutamate Receptors: Design and Therapeutic Prospects. J Med Chem. 2000 Jul 13;43(14):2609-45.
CAS Number: 52809-07-1
Molecular Weight: 189.13
Compound Purity: 98.0
Research Area: Neurological Disease
Solubility: DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)/H2O : 2 mg/mL (ultrasonic;warming;heat to 60°C)
Target: iGluR;mGluR