Product Description: R-7050 (TNF-α Antagonist III) is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFα.
Applications: Cancer-Kinase/protease
Formula: C16H8ClF3N4S
References: [1]Gururaja TL, et al. A class of small molecules that inhibit TNFalpha-induced survival and death pathways viaprevention of interactions between TNFalphaRI, TRADD, and RIP1. Chem Biol. 2007 Oct;14(10):1105-18./[2]King MD, et al. TNF-alpha receptor antagonist, R-7050, improves neurological outcomes following intracerebralhemorrhage in mice. Neurosci Lett. 2013 May 10;542:92-6.
CAS Number: 303997-35-5
Molecular Weight: 380.77
Compound Purity: 98.55
Research Area: Cancer
Solubility: DMSO : 25 mg/mL (ultrasonic)
Target: TNF Receptor