Rabbit anti-CENP-F/Mitosin Antibody Affinity Purified

Stock Concentration: 200 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein Ref Seq ID: NP_057427.3

Uniprot ID: P49454

Background: Centromere protein F (CENP-F) is a microtubule binding protein and component of the kinetochore. It is essential for kinetochore attachment, chromosome alignment, and the spindle checkpoint. CENP-F appears to be important to the association of the NudE-related proteins Ndel1 and Nde1 to the Lis1/dynein motor complex and their role in kinetochore function. CENP-F is a farnesylated protein and the farnesylation of CENP-F appears to be central to its role in mediating kinetochore-microtubule interactions as well as its degradation after mitosis. Recently, CENP-F expression has been correlated with markers of poor outcome in breast cancer.

Immunogen: Between 2275 and 2325

Physical State: Liquid

Purity: Antigen Affinity Purified

Antibody Registry ID: AB_1210907

• Artikelnummer: BEYA301-617A-T
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A301-617A-T
• Verpackungseinheit: 10 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Immunoprecipitation, Western Blotting, Immunohistochemistry
• Isotyp: IgG
• Human Gene ID: 1063
• Wirt: Rabbit
• Konjugat: Unconjugated