Product Description: (Rac)-Finerenone ((Rac)-BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold)[1].
Applications: Neuroscience-Neuromodulation
Formula: C21H22N4O3
References: [1]Bärfacker L, et al. Discovery of BAY 94-8862: a nonsteroidal antagonist of the mineralocorticoid receptor for the treatment of cardiorenal diseases. ChemMedChem. 2012;7(8):1385-1403.
CAS Number: 1050477-27-4
Molecular Weight: 378.42
Compound Purity: 99.66
Research Area: Cardiovascular Disease
Solubility: DMSO : 62.5 mg/mL (ultrasonic)
Target: Mineralocorticoid Receptor