Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: N-[2-[(acetylthio)methyl]-1-oxo-3-phenylpropyl]-glycine, phenylmethyl ester
Purity: ≥98%
Formula Markup: C21H23NO4S
Formula Weight: 385.5
CAS Number: 81110-73-8
Notes: Racecadotril is a prodrug form of the neprilysin (NEP) inhibitor thiorphan (Item No. 15600).{62164,62165} In vivo, racecadotril reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats when administered at doses of 80 or 100 mg/kg, respectively.{62164} It also decreases the duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-induced diarrhea.{62165} Formulations containing racecadotril have been used in the treatment of acute diarrhea.