Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 3,5-bis[(3,4-dichlorophenyl)methylene]-4-piperidinone
Purity: ≥98%
Formula Markup: C19H13Cl4NO
Formula Weight: 413.12346
CAS Number: 145888-79-5
Notes: RAMB4 is an inhibitor of the ubiquitin-proteasome system.{68167} It increases the levels of polyubiquitinated proteins in HeLa cervical cancer cells, but does not inhibit the chymotrypsin-like, trypsin-like, or peptidylglutamyl peptide hydrolyzing-like activities of the 20S proteasome, in cell-free assays when used at a concentration of 10 µM. RAMB4 decreases the viability of HeLa cells (IC50 = 2 µM).