Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-(phenyl-2,3,4,5,6-d5)propyl]amino]-1-oxopropyl]octahydro-cyclopenta[b]pyrrole-2-carboxylic acid
Purity: ≥99% deuterated forms (d1-d5)
Formula Markup: C23H27D5N2O5
Formula Weight: 421.54096
CAS Number: 1132661-86-9
Notes: Ramipril-d5 is intended for use as an internal standard for the quantification of ramipril (Item No. 15558) by GC- or LC-MS. Ramipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor ramiprilat (Item No. 15557).{23056} Ramipril (2.5 mg/kg per day, p.o.) reduces systolic blood pressure in spontaneously hypertensive rats.{36825} It reduces aortic valve backscatter and improves aortic flow in a rabbit model of aortic valve stenosis.{36826} Ramipril also decreases paw swelling and serum levels of TNF-α and prostaglandin E2 (PGE2) as well as cardiac collagen deposition and fibrosis in a rat model of adjuvant-induced arthritis.{36827}
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