Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-methanone, monohydrochloride
Purity: ≥98%
Formula Markup: C17H17N3O / HCl
Formula Weight: 315.8
CAS Number: 132907-72-3
Notes: Ramosetron is a potent and selective antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 0.06 nM).{25619,25621} It has little or no effect at other 5-HT receptor subtypes or at adrenergic or histamine receptors.{25619} Ramosetron competitively blocks serotonin-mediated contraction of the colon.{25619} It has applications in ameliorating diarrhea-predominant inflammatory bowel syndrome and postoperative nausea and vomiting.{25618,25620}