Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N'-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]sulfinyl]ethyl]-N-methyl-2-nitro-1,1-ethenediamine
Purity: ≥90%
Formula Markup: C13H22N4O4S
Formula Weight: 330.40434
CAS Number: 73851-70-4
Notes: Ranitidine S-oxide is a metabolite of the histamine H2 receptor antagonist ranitidine (Item No. 16939).{67071} It is formed via S-oxidation of ranitidine by flavin-containing monooxygenase 3 (FMO3) and FMO5.{67069} Ranitidine S-oxide is acutely cytotoxic to the aquatic species B. calyciflorus and C. dubia (LC50s = 4.51 and 7.85 mg/L, respectively), and it inhibits the reproduction of B. calyciflorus and C. dubia with chronic exposure (EC50s = 0.83 and 0.51 mg/L, respectively).{67070} It is mutagenic to S. typhimurium and genotoxic to E. coli when used at concentrations ranging from 0.312 to 0.625 µg/ml and 0.312 to 5 µg/ml, respectively.
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