Clone Number: BXP-9
Immunogen: BCRP aa 221-394
Concentration: 250 ug/ ml
Storage buffer: cell culture supernatant with 0.7% BSA and 0.1% sodium azide
Additional info: The BXP-9 Mab was selected after immunization with a fusion protein containing the E. coli maltose binding protein and a fragment of the mouse bcrp protein corresponding to amino acids 221-394. BXP-9 reacts with an internal epitope of bcrp, a 70 kD transmembrane half-transporter which is involved in Multidrug resistance. BXP-9 does not react with the human BCRP molecule.
Applications: ICC (1:20-1:50), IHC-fr (1:20), WB (1:50), FC
References: Doyle LA et al. Proc Nat Acad Sci 1998; 95: 15665-15670/Scheffer G et al. Cancer Res. 2000; 60: 2589-2593/Jonker JW et al. Proc Nat Acad Sci 2002; 26: 15649-54