Target Synonym: KCNIP;KCHIP;KCNIP3;CSEN;DREAM;KCHIP3;4933407H12Rik;A type potassium channel modulatory protein 3;AI413860;A-type potassium channel modulatory protein 3;Calsenilin;DRE antagonist modulator;DRE-antagonist modulator;EF hand transcription factor;KCHIP 3;KCNIP 3;Kv channel interacting protein 3;Kv channel-interacting protein 3;MGC18289;Potassium channel interacting protein 3;R74849
Background: This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv1 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.
Immunogen: Recombinant Human CSEN / calsenilin / KCNIP3 Protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: IHC-P 1:250-1:1000;
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