Recombinant Human GM-CSF Protein(His Tag)

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Protein Tag: C-His

Uniprot: P04141

Accession: P04141

Background: CSF2 (Colony Stimulating Factor 2) is a Protein Coding gene. Diseases associated with CSF2 include Mucositis and Candida Glabrata. Among its related pathways are RET signaling and IL-15 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types. GO annotations related to this gene include cytokine activity and granulocyte macrophage colony-stimulating factor receptor binding. The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.

Bio Acitivity: Not validated for activity

Sequence: AIa18-Glu144

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 13.9 kDa

Observed MW: 20-30 kDa

• Artikelnummer: ELSPDMH100207-1
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: PDMH100207-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK