Recombinant Human PTX3 Protein(Fc Tag)

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Protein Tag: C-Fc

Uniprot: P26022

Accession: P26022

Background: Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of “long pentraxins”, which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells.

Bio Acitivity: Not validated for activity

Sequence: Glu18-Ser381

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 64.9 kDa

Observed MW: 60-80 kDa

• Artikelnummer: ELSPDMH100235-1
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: PDMH100235-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK