Recombinant PDHA1 Monoclonal Antibody

Target Synonym: PDHA1;PDHA;PDHAD;PDHCE1A;PHE1A;E1 alpha polypeptide 1;mitochondrial;ODPA;PDH;PDHE1 A type I;PDHE1-A type I;PDHα;Pyruvate Dehydrogenase (lipoamide) alpha 1;Pyruvate dehydrogenase complex;Pyruvate Dehydrogenase E1 alpha;Pyruvate dehydrogenase E1 component subunit alpha;somatic form

Background: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen: Recombinant Human PDHA1 Protein

Buffer: 0.2 μm filtered solution in PBS

Dilution: ICC/IF 1:20-1:100

• Artikelnummer: ELSAN300453P-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: AN300453P-100
• Verpackungseinheit: 100μL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Immunofluorescence, Immunocytochemistry
• Isotyp: IgG
• Wirt: Rabbit
• Konjugat: Unconjugated