Target Synonym: THC;ASV;SRC1;THC6;c-SRC;p60-Src;SRC;pp60c-src;Proto-oncogene c-Src;Proto-oncogene tyrosine-protein kinase Src;Avian sarcoma virus;c SRC;CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA;cSrc;EC 2.7.10.2;Neuronal CSRC tyrosine specific protein kinase;Neuronal SRC;Oncogene SRC;OTTHUMP00000174476;OTTHUMP00000174477;p60 Src;p60Src;pp60c src;pp60csrc;Proto oncogene tyrosine protein kinase Src;Protooncogene SRC;Protooncogene SRC Rous sarcoma;SRC Oncogene;SRC proto oncogene non receptor tyrosine kinase;Tyrosine kinase pp60c src;Tyrosine protein kinase SRC 1;Tyrosine protein kinase SRC1;v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog;V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian);v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian
Background: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Immunogen: A synthetic peptide corresponding to the residues around
Buffer: 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Dilution: WB 1:1000-1:10000
Calculated MW: 60 kDa
Observed MW: 60 kDa
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