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Recombinant Rat EZH1 protein (His tag)

Recombinant Rat EZH1 protein (His tag)
Artikelnummer
ELSPDER100203-100
Verpackungseinheit
100μg
Hersteller
Elabscience Biotechnology

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Protein Tag: N-His

Uniprot: F1LZH3

Accession: F1LZH3

Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates "Lys-27" of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di-and trimethylate "Lys-27" of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

Bio Acitivity: Not validated for activity

Sequence: Lys 201-Ser 400

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.

Calculated MW: 21.9 kDa

Observed MW: 28 kDa
Mehr Informationen
Artikelnummer ELSPDER100203-100
Hersteller Elabscience Biotechnology
Hersteller Artikelnummer PDER100203-100
Verpackungseinheit 100μg
Mengeneinheit STK
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