Remibrutinib, CAS 1787294-07-8

Product Description: Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood[1]. Remibrutinib has the potential for Chronic urticaria (CU) treatment[2].

Applications: COVID-19-immunoregulation

Formula: C27H27F2N5O3

References: [1]Daniela Angst, et al. Novel amino pyrimidine derivatives. Patent WO2015079417A1./[2]Kolkhir P, et al. New treatments for chronic urticaria. Ann Allergy Asthma Immunol. 2019 Aug 23.

CAS Number: 1787294-07-8

Molecular Weight: 507.53

Compound Purity: 99.76

Research Area: Inflammation/Immunology

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Btk

• Artikelnummer: MEXHY-128757-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-128757-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK