Product Description: Rhein is an anthraquinone compound with anti-inflammatory, antioxidant, and anti-cancer effects[1].
Applications: Cancer-Kinase/protease
Formula: C15H8O6
References: [1]Hou ML, et al. The Drug-Drug Effects of Rhein on the Pharmacokinetics and Pharmacodynamics of Clozapine in Rat Brain Extracellular Fluid by In Vivo Microdialysis. J Pharmacol Exp Ther. 2015 Oct;355(1):125-34./[2]Heo SK, et al. Rhein augments ATRA-induced differentiation of acute promyelocytic leukemia cells. Phytomedicine. 2018 Oct 1;49:66-74./[3]Zhao YL, et al. Rhein protects against acetaminophen-induced hepatic and renal toxicity. Food Chem Toxicol. 2011 Aug;49(8):1705-10. /[4]Fernand VE, et al. Rhein inhibits angiogenesis and the viability of hormone-dependent and -independent cancer cells under normoxic or hypoxic conditions in vitro. Chem Biol Interact. 2011 Jul 15;192(3):220-32.
CAS Number: 478-43-3
Molecular Weight: 284.22
Compound Purity: 99.73
Research Area: Cancer; Infection; Inflammation/Immunology
Solubility: 0.1 M NaOH : ≥ 12.5 mg/mL/DMSO : 12.17 mg/mL (ultrasonic;warming)
Target: Apoptosis;Autophagy;Bacterial;Reactive Oxygen Species
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