Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 2ß,3ß-epoxy-grayanotoxane-5,6ß,10,14R,16-pentol
Purity: ≥98%
Formula Markup: C20H32O6
Formula Weight: 368.46448
CAS Number: 26342-66-5
Notes: Rhodojaponin III is a diterpenoid that has been found in R. molle and has insecticidal and antinociceptive activities.{57993,57992} It reduces pupation and the number of Colorado potato beetle (L. decemlineata) larvae on, and damage to, potato plants when applied at concentrations of 75 and 150 ppm.{57993} It also induces mortality in adult confused flour beetles (T. confusum). Rhodojaponin III has antinociceptive effects in mouse models of chemical, inflammatory, and neuropathic pain.{57992} It reduces acetic acid-induced writhing in mice (ID50 = 0.0469 mg/kg) and increases the paw withdrawal threshold for mechanical stimuli in a mouse model of diabetic peripheral neuropathic pain when administered at doses of 0.04 and 0.08 mg/kg. Rhodojaponin III is toxic to mice with an LD50 value of 0.271 mg/kg.
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