RI-2, CAS 1417162-36-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione

Purity: ≥98%

Formula Markup: C21H18Cl2N2O4

Formula Weight: 433.3

CAS Number: 1417162-36-7

Notes: RI-2 is a reversible inhibitor of RAD51 (IC50 = 44.2 µM), a protein that is central to the homologous recombination process initiated upon DNA double-strand breaks and is often overexpressed in a wide range of human cancer cell types.{31181} At 150 µM, it has been shown to inhibit DNA repair and to sensitize cancer cells to cross-linking chemotherapy in vitro.{31181}

• Artikelnummer: CAY18397-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 18397-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK