Riluzole (hydrochloride), CAS 850608-87-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 6-(trifluoromethoxy)-2-benzothiazolamine, monohydrochloride

Purity: ≥98%

Formula Markup: C8H5F3N2OS / HCl

Formula Weight: 270.7

CAS Number: 850608-87-6

Notes: Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM).{22851} Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg.{22851} Formulations containing riluzole have been explored as therapeutics for slowing disease progression of amyotrophic lateral sclerosis.{22851}

• Artikelnummer: CAY14577-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 14577-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK