RIPK1-IN-7, CAS 2300982-44-7

Product Description: RIPK1-IN-7 is a potent and selective RIPK1 inhibitor with a Kd of 4 nM and an enzymatic IC50 of 11 nM. RIPK1-IN-7 exhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model[1].

Applications: Cancer-Kinase/protease

Formula: C25H22F3N5O2

References: [1]Li Y, et al. Identification of 5-(2,3-Dihydro-1 H-indol-5-yl)-7 H-pyrrolo[2,3- d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model. J Med Chem. 2018 Dec 27;61(24):11398-11414.

CAS Number: 2300982-44-7

Molecular Weight: 481.47

Compound Purity: 98.56

Research Area: Cancer

Solubility: DMSO : 62.5 mg/mL (ultrasonic)

Target: RIP kinase

• Artikelnummer: MEXHY-119933-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-119933-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK