Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: glycyl-L-arginylglycyl-3-sulfo-L-alanyl-L-threonyl-L-proline, trifluoroacetate salt
Purity: ≥95%
Formula Markup: C22H39N9O11S / XCF3COOH
Formula Weight: 637.66512
Notes: Risuteganib is an anti-integrin peptide and a derivative of RGD peptide (Item No. 14501).{61287} Risuteganib (400 µM) protects against hydroquinone-induced necrosis and apoptosis, as well as inhibits hydroquinone-induced production of reactive oxygen species (ROS), in human retinal pigment epithelial (RPE) cells.{61288} It decreases the expression of BAX, VEGFA, and ITB1 in human age-related macular degeneration (AMD) cybrid cell lines when used at a concentration of 20 mg/ml.{61289} Risuteganib arrests aberrant blood vessel growth mediated by αVβ3, αVβ5, and α5β1 integrins in vivo.{61287}