Zoldonrasib, CAS 2922732-54-3

Product Description: RMC-9805 (KRAS G12D inhibitor 18) is a KRAS G12D inhibitor. RMC-9805 is orally active. RMC-9805 inhibits RAS signaling to induce apoptosis in KRAS G12D mutant cancer cells[1][2].

Formula: C63H88F3N11O7

References: [1]BLAKE JAMES F, et al. Preparation of peptide-linked macrocyclic dipeptides as Ras inhibitors.World Intellectual Property Organization, WO2023060253 A1 2023-04-13/[2]Knox, J et al.RMC-9805, a first-in-class, mutant-selective, covalent and orally bioavailable KRASG12D(ON) inhibitor, promotes cancer-associated neoantigen recognition and synergizes with immunotherapy in preclinical models. Cancer Res 1 April 2023; 83 (7_Supplement): 3475

CAS Number: 2922732-54-3

Molecular Weight: 1168.44

Compound Purity: 99.73

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Ras

• Artikelnummer: MEXHY-156819-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-156819-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK